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Lung penetration of methylprednisolone

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A husband and wife, both emergency room physicians, presented with toxic ingestion of the drug. The year-old husband called EMS after his wife, age 33, developed vomiting and diarrhea, followed by a witnessed seizure. Upon arrival to the hospital, the patients manifested severe cyanosis and were hypotensive and hypoxemic despite high flow oxygen. Methemoglobinemia is a condition in which oxidation of ferrous iron creates an altered state of hemoglobin that is unable to adequately unload oxygen, resulting in tissue hypoxia. The patients received IV methylene blue and hydration, and all symptoms resolved within 6 hours of presentation.
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Availability Prescription only. Two hundred thirteen patients were excluded because they were already receiving hydrocortisone for hemodynamic stabilization of refractory septic shock on high-dose vasopressors. Also tell your doctor if you have diabetes. Chemicals in tobacco smoke can cause — among many other health problems — inflammation and damage to the air sacs.
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Steroids in pneumonia and ARDS

Pulmonary surfactant is a surface-active lipoprotein complex phospholipoprotein formed by type II alveolar cells. The proteins and lipids that surfactant comprises have both a hydrophilic region and a hydrophobic region. By adsorbing to the air-water interface of alveoli with the hydrophilic head groups in the water and the hydrophobic tails facing towards the air, the main lipid component of surfactant, dipalmitoylphosphatidylcholine DPPC , reduces surface tension.
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Generic Name: lidocaine hydrochloride, bupivacaine hydrochloride, and methylprednisolone acetate Dosage Form: injection. Lidocaine Hydrochloride Injection, USP is a sterile, nonpyrogenic solution of lidocaine hydrochloride in water for injection for parenteral administration in various concentrations with characteristics as follows:. Multiple-dose vials contain 0.

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